Abstract Search

ea0021p123 | Cytokines and growth factors | SFEBES2009

Interaction of endothelin, aldosterone and bone morphogenetic proteins on mitotic actions of pulmonary arterial smooth muscle cells isolated from pulmonary arterial hypertension

Otsuka Fumio , Yamanaka Ryutaro , Nakamura Kazufumi , Yamashita Misuzu , Takeda Masaya , Suzuki Jiro , Miyoshi Tomoko , Inagaki Kenichi , Makino Hirofumi

Primary arterial hypertension (PAH) is a life-threatening disease that has prevalence of 1 to 2 occurrences per one million individuals. This disease is characterized by excessive proliferation of vascular endothelium and smooth muscle cells, causing thickening the walls of pulmonary arterioles. Recent studies have uncovered a link between familial and idiopathic PAH to BMPRII mutations. The pathology of PAH is characterized by the remodeling of pulmonary arteries due to pulmo...

0 shares

Endocrine Abstracts

Interaction of endothelin, aldosterone and bone morphogenetic proteins on mitotic actions of pulmonary arterial smooth muscle cells isolated from pulmonary arterial hypertension

BiosciAbstracts